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To the best of the authors’ knowledge, no study has previously examined the use of psychoactive substances (PASs) at electronic dance music (EDM) events in Ukraine. Addressing this gap in the research literature, this study aims to: describe the recreational drug scene associated with Ukrainian EDM culture; identify clusters of EDM participants who use PAS, based on their drug use patterns; and assess the uptake of drug checking and investigate associations between drug checking and subsequent drug-related behaviour.

A series of cross-sectional surveys were conducted in 2021 (N = 1,307) among EDM festival participants in Ukraine. The authors performed cluster analysis to identify distinct profiles of PAS users. Trends in drug checking were analysed based on cross-sectional surveys conducted at one recurring festival in 2018 (N = 99), 2019 (N = 195) and 2021 (N = 237).

The substances most often used at EDM events were 3,4-Methylenedioxymethamphetamine (37%), amphetamine (16%), lysergic acid diethylamide (11%) and cocaine (9%). Between 2018 and 2021, the proportion of participants who reported to have ever tested their drugs has increased from 2% to 26% (p < 0.001). Unexpected or inconclusive test results led to a significantly lower chances of drug consumption (p = 0.003). The authors identified three distinct clusters of PAS users among the EDM festival attendees in Ukraine.

This study will inform the development of harm reduction interventions tailored to various subgroups of recreational PAS users taking into account gender-specific patterns of use suggested by the authors’ cluster analysis. Increased availability of drug checking is crucial to reduce the risks of drug-related harm associated with the consumption of mis-sold, mislabeled and/or adulterated substances.